|Title||Associate Professor with Secondary Appointment in The Center for Metabolism and Obesity Research|
Mechanisms governing metabolic homeostasis; function of adipose-and skeletal muscle-derived hormones; mechanisms of insulin resistance and type 2 Diabetes
Our lab seeks to understand mechanisms employed by cells and tissues to maintain metabolic homeostasis. We are currently addressing how adipose- and skeletal muscle-derived hormones (adipokines and myokines), discovered in our lab, regulate tissue crosstalk and signaling pathways to control energy metabolism. Transgenic and knockout mouse models, as well as cell culture systems, are used to address the role of CTRP family of hormones in physiological and disease states. We also aim to identify the receptors that mediate the biological functions of CTRPs.