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The research mission of the Department of Physiology is to explore how the complex cellular phenotypes that underlie the integrated functions of the tissues and organ systems comprising higher living organisms, emerge from the genomic code.

The origins of the Department of Physiology at the Johns Hopkins School of Medicine began with H. Newell Martin, Sc.D. (1843-1893) who, in 1883, was Professor of Biology.  Martin was a former student of the great 19th century biologist Thomas Huxley, one of the earliest proponents of Darwin’s theory of evolution.

Our research program extends from computational methods to developmental genetics and post-genomic strategies—from bacteria and yeast, to zebrafish, mouse, and man.

William Guggino, Ph.D.

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